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Human single B cell antibody technology
Human single B cell antibody technology is an attractive and efficient approach to discovery human monoclonal antibody from vaccine recipients or convalescent patients. The standard process included the screening of antigen-specific memory B cells, the amplification of variable region, the construction of expression vector, the production and characterization of mAbs.
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Phage display
Phage display is a technology to insert the DNA sequence of foreign protein or peptide into the appropriate position of phage coat protein structural gene, so the exogenous gene can be expressed and shown on the surface of phage. By using this technology, a phage library can be established to express a wide diversity of peptides or proteins and can be used to select those binding to the desired targets.
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Human antibody mouse
AcadeMab’s antibody mouse is to replace the original mouse antibody genes by human antibody genes.
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AM-D001 (Anti-M13 antibody)
Human single B cell antibody technology is an attractive and efficient approach to discovery human monoclonal antibody from vaccine recipients or convalescent patients.
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